Medicine

Progressing ASO treatments coming from progression to implementation

.Completing rate of interests.R.S., M.S., H.G. and A.A.R. are planners of the 1M1M initiative. H.G. as well as A.A.R. are actually board of directors participants and R.S., M.S. as well as A.A.R. are participants of the scientific advisory board of N1C. A.A.R. reveals employment by LUMC, which has licenses on exon-skipping technology, some of which has actually been actually licensed to BioMarin and consequently sublicensed to Sarepta. As co-inventor of several of these patents, A.A.R. was actually qualified to a reveal of aristocracies. A.A.R. further discloses acting as impromptu professional for PTC Therapies, Sarepta Rehabs, Regenxbio, Dyne Rehabs, Lilly, BioMarin Pharmaceuticals Inc., Eisai, Entrada, Takeda, Splicesense, Galapagos, Sapreme, Italfarmaco and Astra Zeneca. Over the last 5 years, A.A.R. also carried out speaking to for Alpha Anomeric. A.A.R. additionally states membership of the clinical boards of advisers of Eisai, Hybridize Rehabs, Silence Therapies, Sarepta Therapeutics, Sapreme and also Mitorx. In the past 5 years, A.A.R. was also a clinical board of advisers member for ProQR. Wage for A.A.R. u00e2 s consulting as well as recommending tasks is actually spent to LUMC. Over the last 5 years, LUMC likewise received sound speaker gratuity coming from PTC Therapies, Alnylam Netherlands, Italfarmaco and also Pfizer and funding for contract research from Sapreme, Eisai, Galapagos, Synaffix and Alpha Anomeric. Task funding is acquired from Sarepta Therapeutics and also Entrada by means of unlimited grants. H.G. has absolutely nothing to divulge relative to the subjects covered in this particular document. Before 5 years, he has actually also obtained consultancy gratuity coming from UCB. M.S. got working as a consultant gratuity from Ionis, UCB, Prevail, Orphazyme, Biogen, Servier, Reata, GenOrph, AviadoBio, Biohaven, Zevra, Lilly as well as Solaxa before 5 years, all irrelevant to the present manuscript. R.S. has absolutely nothing to make known in relation to the subjects covered in this particular document. She has actually gotten audio speaker and/or working as a consultant gratuity or even sponsoring payments from Abbvie, Bial, STADA and Everpharma in the past 5 years.